The prison is a specialized operating environment that is designed, in part, to facilitate the flow of foods and pharmaceuticals through incarcerated bodies, a movement of biotechnologies that creates patterned effects on populations and the ecologies in which they are enmeshed. These biotechnologies are deployed tactically within specially engineered carceral environments as means by which the State can meet its constitutional obligations to provide for basic human sustenance. How does this conceptualization of prisons as operating environments for biotechnologies change how we think, analyze, and challenge carcerality? This paper articulates how carceral environments link capitalist structures of prison commodity provision to raw needs for human and planetary survival. I offer two descriptive claims. First, foods and pharmaceuticals reconfigure the embodied, social, and psychic lives of incarcerated people as they are forced to live in carceral space. Second, the movement of industrialized quantities of food and pharmaceuticals through prisons creates ecological externalities that contribute to systematic environmental degradation and climate change. When considered together, the analysis of foods and pharmaceuticals as biotechnologies reveals the design features of incarceration and opens possibilities for abolitionist responses to mass captivity.